1.Responsible for history taking and monitoring of vitals. 2. Responsible for E.C.G recording. 3. Responsible for Blood Sample Collection and Processing. 4. Responsible to perform Urine Scan for Drug of Abuse and Breath Alcohol Test. 5. Assists the Physician in case of emergency. 6. Maintain the ICU and its equipment. 7. Responsible to perform custodian activities during study. 8. Assist in Screening activities. 9. Responsible for Administration of Investigation Product .